| 1 |  Amgen Inc.AMGN | Biological Products, (No Diagnostic Substances) | $182.28 B |
| 2 |  Gilead Sciences, Inc.GILD | Biological Products, (No Diagnostic Substances) | $150.83 B |
| 3 | Aargenx SEARGX | Biological Products, (No Diagnostic Substances) | $53.35 B |
| 4 | RRevolution Medicines, Inc.RVMD | Biological Products, (No Diagnostic Substances) | $30.65 B |
| 5 |  IQVIA Holdings Inc.IQV | Services-Commercial Physical & Biological Research | $30.40 B |
| 6 |  Biogen Inc.BIIB | Biological Products, (No Diagnostic Substances) | $28.68 B |
| 7 |  BioNTech SEBNTX | Biological Products, (No Diagnostic Substances) | $21.79 B |
| 8 |  Incyte CorporationINCY | Services-Commercial Physical & Biological Research | $21.06 B |
| 9 |  Moderna, Inc.MRNA | Biological Products, (No Diagnostic Substances) | $18.25 B |
| 10 |  Neurocrine Biosciences, Inc.NBIX | Biological Products, (No Diagnostic Substances) | $16.17 B |
| 11 |  Medpace Holdings, Inc.MEDP | Services-Commercial Physical & Biological Research | $13.30 B |
| 12 |  Exelixis, Inc.EXEL | Biological Products, (No Diagnostic Substances) | $13.22 B |
| 13 | IICON Public Limited CompanyICLR | Services-Commercial Physical & Biological Research | $11.04 B |
| 14 |  Krystal Biotech, Inc.KRYS | Biological Products, (No Diagnostic Substances) | $9.21 B |
| 15 |  Charles River Laboratories International, Inc.CRL | Services-Commercial Physical & Biological Research | $8.97 B |
| 16 |  Halozyme Therapeutics, Inc.HALO | Biological Products, (No Diagnostic Substances) | $8.36 B |
| 17 |  Bio-Techne CorporationTECH | Biological Products, (No Diagnostic Substances) | $8.22 B |
| 18 |  Qiagen N.V.QGEN | Biological Products, (No Diagnostic Substances) | $8.03 B |
| 19 |  Repligen CorporationRGEN | Biological Products, (No Diagnostic Substances) | $7.38 B |
| 20 | IImmunityBio, Inc.IBRX | Biological Products, (No Diagnostic Substances) | $7.31 B |
| 21 | AArcellxACLX | Biological Products, (No Diagnostic Substances) | $6.73 B |
| 22 | PVaxcyte, Inc.PCVX | Biological Products, (No Diagnostic Substances) | $6.56 B |
| 23 |  Kymera Therapeutics, Inc.KYMR | Biological Products, (No Diagnostic Substances) | $6.44 B |
| 24 | IImmunovant, Inc.IMVT | Biological Products, (No Diagnostic Substances) | $6.40 B |
| 25 | AApogee Therapeutics, Inc.APGE | Biological Products, (No Diagnostic Substances) | $6.19 B |
| 26 | SScholar Rock Holding CorporationSRRK | Biological Products, (No Diagnostic Substances) | $5.28 B |
| 27 | CCG Oncology, Inc.CGON | Biological Products, (No Diagnostic Substances) | $4.84 B |
| 28 |  CRISPR Therapeutics AGCRSP | Biological Products, (No Diagnostic Substances) | $4.77 B |
| 29 |  Twist Bioscience CorporationTWST | Biological Products, (No Diagnostic Substances) | $4.22 B |
| 30 | DDenali Therapeutics Inc.DNLI | Biological Products, (No Diagnostic Substances) | $3.27 B |
| 31 |  Beam Therapeutics Inc.BEAM | Biological Products, (No Diagnostic Substances) | $3.03 B |
| 32 |  Adaptive Biotechnologies CorporationADPT | Biological Products, (No Diagnostic Substances) | $2.73 B |
| 33 | TTarsus Pharmaceuticals, Inc.TARS | Biological Products, (No Diagnostic Substances) | $2.64 B |
| 34 |  Relay Therapeutics, Inc.RLAY | Biological Products, (No Diagnostic Substances) | $2.58 B |
| 35 |  BioCryst Pharmaceuticals, Inc.BCRX | Biological Products, (No Diagnostic Substances) | $2.08 B |
| 36 |  Mesoblast LimitedMESO | Biological Products, (No Diagnostic Substances) | $1.99 B |
| 37 | KKodiak Sciences Inc.KOD | Biological Products, (No Diagnostic Substances) | $1.97 B |
| 38 | AADMA Biologics, Inc.ADMA | Biological Products, (No Diagnostic Substances) | $1.97 B |
| 39 |  Vericel CorporationVCEL | Biological Products, (No Diagnostic Substances) | $1.91 B |
| 40 |  Iovance Biotherapeutics, Inc.IOVA | Biological Products, (No Diagnostic Substances) | $1.69 B |
| 41 |  Ethos Technologies Inc.LIFE | Biological Products, (No Diagnostic Substances) | $1.62 B |
| 42 |  Recursion Pharmaceuticals, Inc.RXRX | Biological Products, (No Diagnostic Substances) | $1.61 B |
| 43 | TTaysha Gene Therapies, Inc.TSHA | Biological Products, (No Diagnostic Substances) | $1.55 B |
| 44 | IInhibrx Biosciences, Inc.INBX | Biological Products, (No Diagnostic Substances) | $1.53 B |
| 45 | IImmunocore Holdings plcIMCR | Biological Products, (No Diagnostic Substances) | $1.42 B |
| 46 |  Novavax, Inc.NVAX | Biological Products, (No Diagnostic Substances) | $1.41 B |
| 47 |  Monte Rosa Therapeutics, Inc.GLUE | Biological Products, (No Diagnostic Substances) | $1.40 B |
| 48 | VVir Biotechnology, Inc.VIR | Biological Products, (No Diagnostic Substances) | $1.39 B |
| 49 | MMaze Therapeutics, Inc.MAZE | Biological Products, (No Diagnostic Substances) | $1.31 B |
| 50 | AAlvotechALVO | Biological Products, (No Diagnostic Substances) | $1.29 B |
| 51 | CHemab Therapeutics Holdings, Inc.COAG | Biological Products, (No Diagnostic Substances) | $1.19 B |
| 52 |  Immatics N.V.IMTX | Biological Products, (No Diagnostic Substances) | $1.19 B |
| 53 |  DBV Technologies S.A.DBVT | Biological Products, (No Diagnostic Substances) | $1.11 B |
| 54 | AAbsci CorporationABSI | Services-Commercial Physical & Biological Research | $994.67 M |
| 55 |  Cullinan Therapeutics, Inc.CGEM | Biological Products, (No Diagnostic Substances) | $740.57 M |